I made an educational Video about PCR using the paper tactile model I designed in 2009. To the best of my knowledge, this is the only hands-on PCR learning tool around, so I decided to make a video showing how to use it.
You can download, print, cut-out, and tape together your own model! I have found that it helps the students I’ve mentored understand.
The novel concept behind the paper model is that the primer has a string hanging off the 3′ end, and the dNTPs are beads. So, to start making a strand of DNA, you need to start with a primer (because it has the string). DNA replication also has to start with a primer. Watch the video above if you want to learn more about it.
I taped the video in my living room using a webcam and a headset microphone. I edited the video in Adobe Premiere. Finding music for your videos is real challenge these days. I chose fan-recorded music from a live Grateful Dead concert, because it’s my understanding is that the Grateful Dead allows people to use that without copyright penalty.